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Polygenic signals of sex differences in selection in humans from the UK Biobank

Sex differences in the fitness effects of genetic variants can influence the rate of adaptation and the maintenance of genetic variation. For example, “sexually antagonistic” (SA) variants, which are beneficial for one sex and harmful for the other, can both constrain adaptation and increase genetic...

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Detalles Bibliográficos
Autores principales: Ruzicka, Filip, Holman, Luke, Connallon, Tim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9481184/
https://www.ncbi.nlm.nih.gov/pubmed/36067235
http://dx.doi.org/10.1371/journal.pbio.3001768