Tacrolimus Concentration Is Effectively Predicted Using Combined Clinical and Genetic Factors in the Perioperative Period of Kidney Transplantation and Associated with Acute Rejection

BACKGROUND: Tacrolimus has unpredictable pharmacokinetic (PK) characteristics, which are partially attributed to CYP3A5 polymorphism. The potential effects of clinical factors in the postoperative period of transplantation on tacrolimus PK and those of early tacrolimus PK variability on clinical out...

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Detalles Bibliográficos
Autores principales: Cheng, Fang, Li, Qiang, Cui, Zheng, Wang, Zhendi, Zeng, Fang, Zhang, Yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9481373/
https://www.ncbi.nlm.nih.gov/pubmed/36118414
http://dx.doi.org/10.1155/2022/3129389

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9481373/
https://www.ncbi.nlm.nih.gov/pubmed/36118414
http://dx.doi.org/10.1155/2022/3129389

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