Loss of FGFR4 promotes the malignant phenotype of PDAC

Transcriptomic analyses of pancreatic ductal adenocarcinoma (PDAC) have identified two major epithelial subtypes with distinct biology and clinical behaviours. Here, we aimed to clarify the role of FGFR1 and FGFR4 in the definition of aggressive PDAC phenotypes. We found that the expression of FGFR4...

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Detalles Bibliográficos
Autores principales: D’Agosto, Sabrina, Pezzini, Francesco, Veghini, Lisa, Delfino, Pietro, Fiorini, Claudia, Temgue Tane, Gael D., Del Curatolo, Anais, Vicentini, Caterina, Ferrari, Giorgia, Pasini, Davide, Andreani, Silvia, Lupo, Francesca, Fiorini, Elena, Lorenzon, Giulia, Lawlor, Rita T., Rusev, Borislav, Malinova, Antonia, Luchini, Claudio, Milella, Michele, Sereni, Elisabetta, Pea, Antonio, Bassi, Claudio, Bailey, Peter, Scarpa, Aldo, Bria, Emilio, Corbo, Vincenzo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9481460/
https://www.ncbi.nlm.nih.gov/pubmed/35963908
http://dx.doi.org/10.1038/s41388-022-02432-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9481460/
https://www.ncbi.nlm.nih.gov/pubmed/35963908
http://dx.doi.org/10.1038/s41388-022-02432-5

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