Brain-enriched RagB isoforms regulate the dynamics of mTORC1 activity through GATOR1 inhibition

Mechanistic target of rapamycin complex 1 (mTORC1) senses nutrient availability to appropriately regulate cellular anabolism and catabolism. During nutrient restriction, different organs in an animal do not respond equally, with vital organs being relatively spared. This raises the possibility that...

Descripción completa

Detalles Bibliográficos
Autores principales: Figlia, Gianluca, Müller, Sandra, Hagenston, Anna M., Kleber, Susanne, Roiuk, Mykola, Quast, Jan-Philipp, ten Bosch, Nora, Carvajal Ibañez, Damian, Mauceri, Daniela, Martin-Villalba, Ana, Teleman, Aurelio A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9481464/
https://www.ncbi.nlm.nih.gov/pubmed/36097071
http://dx.doi.org/10.1038/s41556-022-00977-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9481464/
https://www.ncbi.nlm.nih.gov/pubmed/36097071
http://dx.doi.org/10.1038/s41556-022-00977-x

Ejemplares similares