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Stem cell-derived synthetic embryos self-assemble by exploiting cadherin codes and cortical tension

Mammalian embryos sequentially differentiate into trophectoderm and an inner cell mass, the latter of which differentiates into primitive endoderm and epiblast. Trophoblast stem (TS), extraembryonic endoderm (XEN) and embryonic stem (ES) cells derived from these three lineages can self-assemble into...

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Detalles Bibliográficos
Autores principales: Bao, Min, Cornwall-Scoones, Jake, Sanchez-Vasquez, Estefania, Cox, Andy L., Chen, Dong-Yuan, De Jonghe, Joachim, Shadkhoo, Shahriar, Hollfelder, Florian, Thomson, Matt, Glover, David M., Zernicka-Goetz, Magdalena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9481465/
https://www.ncbi.nlm.nih.gov/pubmed/36100738
http://dx.doi.org/10.1038/s41556-022-00984-y