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Stem cell-derived synthetic embryos self-assemble by exploiting cadherin codes and cortical tension
Mammalian embryos sequentially differentiate into trophectoderm and an inner cell mass, the latter of which differentiates into primitive endoderm and epiblast. Trophoblast stem (TS), extraembryonic endoderm (XEN) and embryonic stem (ES) cells derived from these three lineages can self-assemble into...
Autores principales: | Bao, Min, Cornwall-Scoones, Jake, Sanchez-Vasquez, Estefania, Cox, Andy L., Chen, Dong-Yuan, De Jonghe, Joachim, Shadkhoo, Shahriar, Hollfelder, Florian, Thomson, Matt, Glover, David M., Zernicka-Goetz, Magdalena |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9481465/ https://www.ncbi.nlm.nih.gov/pubmed/36100738 http://dx.doi.org/10.1038/s41556-022-00984-y |
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