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The effects of AUT00206, a novel Kv3.1/3.2 potassium channel modulator, on task-based reward system activation: a test of mechanism in schizophrenia

The pathophysiology of schizophrenia involves abnormal reward processing, thought to be due to disrupted striatal and dopaminergic function. Consistent with this hypothesis, functional magnetic resonance imaging (fMRI) studies using the monetary incentive delay (MID) task report hypoactivation in th...

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Detalles Bibliográficos
Autores principales: Kaar, Stephen J., Angelescu, Ilinca, Nour, Matthew M., Marques, Tiago Reis, Sharman, Alice, Sajjala, Anil, Hutchison, John, McGuire, Philip, Large, Charles, Howes, Oliver D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9481488/
https://www.ncbi.nlm.nih.gov/pubmed/36094619
http://dx.doi.org/10.1007/s00213-022-06216-3