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The effects of AUT00206, a novel Kv3.1/3.2 potassium channel modulator, on task-based reward system activation: a test of mechanism in schizophrenia
The pathophysiology of schizophrenia involves abnormal reward processing, thought to be due to disrupted striatal and dopaminergic function. Consistent with this hypothesis, functional magnetic resonance imaging (fMRI) studies using the monetary incentive delay (MID) task report hypoactivation in th...
Autores principales: | Kaar, Stephen J., Angelescu, Ilinca, Nour, Matthew M., Marques, Tiago Reis, Sharman, Alice, Sajjala, Anil, Hutchison, John, McGuire, Philip, Large, Charles, Howes, Oliver D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9481488/ https://www.ncbi.nlm.nih.gov/pubmed/36094619 http://dx.doi.org/10.1007/s00213-022-06216-3 |
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