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Genetics and epigenetics: paternal adolescent ethanol consumption in serotonin transporter knock-out rats and offspring sensitivity to ethanol

RATIONALE: Alcohol use disorder (AUD) is shown to have an overall heritability of around 50%. One of the genes associated with AUD is SLC6A4 (solute carrier family 6 member A4) which codes for the serotonin transporter (SERT). The study looked at serotonin dysfunction on ethanol consumption in adole...

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Detalles Bibliográficos
Autores principales: Hussain, Sahir, Lesscher, Heidi M. D., Day, Darren J., Ellenbroek, Bart A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9481507/
https://www.ncbi.nlm.nih.gov/pubmed/35939082
http://dx.doi.org/10.1007/s00213-022-06195-5