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The interaction between LC8 and LCA5 reveals a novel oligomerization function of LC8 in the ciliary-centrosome system

Dynein light chain LC8 is a small dimeric hub protein that recognizes its partners through short linear motifs and is commonly assumed to drive their dimerization. It has more than 100 known binding partners involved in a wide range of cellular processes. Recent large-scale interaction studies sugge...

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Detalles Bibliográficos
Autores principales: Szaniszló, Tamás, Fülöp, Máté, Pajkos, Mátyás, Erdős, Gábor, Kovács, Réka Ágnes, Vadászi, Henrietta, Kardos, József, Dosztányi, Zsuzsanna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9481538/
https://www.ncbi.nlm.nih.gov/pubmed/36114230
http://dx.doi.org/10.1038/s41598-022-19454-4