Enzymatic synthesis of benzylisoquinoline alkaloids using a parallel cascade strategy and tyrosinase variants

Benzylisoquinoline alkaloid derived pharmaceuticals are widely applied in modern medicines. Recent studies on the microbial production of benzylisoquinolines have highlighted key biological syntheses towards these natural products. Routes to non-natural benzylisoquinolines have been less explored, p...

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Detalles Bibliográficos
Autores principales: Wang, Yu, Subrizi, Fabiana, Carter, Eve M., Sheppard, Tom D., Ward, John M., Hailes, Helen C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9481557/
https://www.ncbi.nlm.nih.gov/pubmed/36114194
http://dx.doi.org/10.1038/s41467-022-33122-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9481557/
https://www.ncbi.nlm.nih.gov/pubmed/36114194
http://dx.doi.org/10.1038/s41467-022-33122-1

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