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The marine natural product mimic MPM-1 is cytolytic and induces DAMP release from human cancer cell lines

Bioprospecting contributes to the discovery of new molecules with anticancer properties. Compounds with cytolytic activity and the ability to induce immunogenic cell death can be administered as intratumoral injections with the aim to activate anti-tumor immune responses by causing the release of tu...

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Detalles Bibliográficos
Autores principales: von Hofsten, Susannah, Paulsen, Marianne Hagensen, Magnussen, Synnøve Norvoll, Ausbacher, Dominik, Kranz, Mathias, Bayer, Annette, Strøm, Morten B., Berge, Gerd
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9481558/
https://www.ncbi.nlm.nih.gov/pubmed/36114339
http://dx.doi.org/10.1038/s41598-022-19597-4