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The marine natural product mimic MPM-1 is cytolytic and induces DAMP release from human cancer cell lines
Bioprospecting contributes to the discovery of new molecules with anticancer properties. Compounds with cytolytic activity and the ability to induce immunogenic cell death can be administered as intratumoral injections with the aim to activate anti-tumor immune responses by causing the release of tu...
Autores principales: | von Hofsten, Susannah, Paulsen, Marianne Hagensen, Magnussen, Synnøve Norvoll, Ausbacher, Dominik, Kranz, Mathias, Bayer, Annette, Strøm, Morten B., Berge, Gerd |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9481558/ https://www.ncbi.nlm.nih.gov/pubmed/36114339 http://dx.doi.org/10.1038/s41598-022-19597-4 |
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