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Reconstituted TAD-size chromatin fibers feature heterogeneous nucleosome clusters

Large topologically associated domains (TADs) contain irregularly spaced nucleosome clutches, and interactions between such clutches are thought to aid the compaction of these domains. Here, we reconstituted TAD-sized chromatin fibers containing hundreds of nucleosomes on native source human and lam...

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Detalles Bibliográficos
Autores principales: Korolev, Nikolay, Zinchenko, Anatoly, Soman, Aghil, Chen, Qinming, Wong, Sook Yi, Berezhnoy, Nikolay V., Basak, Rajib, van der Maarel, Johan R. C., van Noort, John, Nordenskiöld, Lars
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9481575/
https://www.ncbi.nlm.nih.gov/pubmed/36114220
http://dx.doi.org/10.1038/s41598-022-19471-3