Chondrogenic primed extracellular vesicles activate miR-455/SOX11/FOXO axis for cartilage regeneration and osteoarthritis treatment

Osteoarthritis (OA) is the leading cause of disability worldwide. Considerable progress has been made using stem-cell-derived therapy. Increasing evidence has demonstrated that the therapeutic effects of BMSCs in chondrogenesis could be attributed to the secreted small extracellular vesicles (sEVs)....

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Detalles Bibliográficos
Autores principales: Sun, Ye, Zhao, Jie, Wu, Qiang, Zhang, Yuxin, You, Yongqing, Jiang, Wenbo, Dai, Kerong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9481593/
https://www.ncbi.nlm.nih.gov/pubmed/36114225
http://dx.doi.org/10.1038/s41536-022-00250-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9481593/
https://www.ncbi.nlm.nih.gov/pubmed/36114225
http://dx.doi.org/10.1038/s41536-022-00250-7

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