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Chondrogenic primed extracellular vesicles activate miR-455/SOX11/FOXO axis for cartilage regeneration and osteoarthritis treatment
Osteoarthritis (OA) is the leading cause of disability worldwide. Considerable progress has been made using stem-cell-derived therapy. Increasing evidence has demonstrated that the therapeutic effects of BMSCs in chondrogenesis could be attributed to the secreted small extracellular vesicles (sEVs)....
Autores principales: | Sun, Ye, Zhao, Jie, Wu, Qiang, Zhang, Yuxin, You, Yongqing, Jiang, Wenbo, Dai, Kerong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9481593/ https://www.ncbi.nlm.nih.gov/pubmed/36114225 http://dx.doi.org/10.1038/s41536-022-00250-7 |
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