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Serum neutralization activity declines but memory B cells persist after cure of chronic hepatitis C

The increasing incidence of hepatitis C virus (HCV) infections underscores the need for an effective vaccine. Successful vaccines to other viruses generally depend on a long-lasting humoral response. However, data on the half-life of HCV-specific responses are lacking. Here we study archived sera an...

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Detalles Bibliográficos
Autores principales: Nishio, Akira, Hasan, Sharika, Park, Heiyoung, Park, Nana, Salas, Jordan H., Salinas, Eduardo, Kardava, Lela, Juneau, Paul, Frumento, Nicole, Massaccesi, Guido, Moir, Susan, Bailey, Justin R., Grakoui, Arash, Ghany, Marc G., Rehermann, Barbara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9481596/
https://www.ncbi.nlm.nih.gov/pubmed/36114169
http://dx.doi.org/10.1038/s41467-022-33035-z