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Identification of a pleiotropic effect of ADIPOQ on cardiac dysfunction and Alzheimer’s disease based on genetic evidence and health care records

Observations of comorbidity in heart diseases, including cardiac dysfunction (CD) are increasing, including and cognitive impairment, such as Alzheimer’s disease and dementia (AD/D). This comorbidity might be due to a pleiotropic effect of genetic variants shared between CD and AD/D. Here, we valida...

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Detalles Bibliográficos
Autores principales: Paik, Hyojung, Lee, Junehawk, Jeong, Chan-Seok, Park, Jun Sung, Lee, Jeong Ho, Rappoport, Nadav, Kim, Younghoon, Sohn, Hee-Young, Jo, Chulman, Kim, Jimin, Cho, Seong Beom
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9481623/
https://www.ncbi.nlm.nih.gov/pubmed/36114174
http://dx.doi.org/10.1038/s41398-022-02144-0