Imprinting fidelity in mouse iPSCs depends on sex of donor cell and medium formulation

Reprogramming of somatic cells into induced Pluripotent Stem Cells (iPSCs) is a major leap towards personalised approaches to disease modelling and cell-replacement therapies. However, we still lack the ability to fully control the epigenetic status of iPSCs, which is a major hurdle for their downst...

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Detalles Bibliográficos
Autores principales: Arez, Maria, Eckersley-Maslin, Melanie, Klobučar, Tajda, von Gilsa Lopes, João, Krueger, Felix, Mupo, Annalisa, Raposo, Ana Cláudia, Oxley, David, Mancino, Samantha, Gendrel, Anne-Valerie, Bernardes de Jesus, Bruno, da Rocha, Simão Teixeira
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9481624/
https://www.ncbi.nlm.nih.gov/pubmed/36114205
http://dx.doi.org/10.1038/s41467-022-33013-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9481624/
https://www.ncbi.nlm.nih.gov/pubmed/36114205
http://dx.doi.org/10.1038/s41467-022-33013-5

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