Physiological calcium combined with electrical pacing accelerates maturation of human engineered heart tissue

Human-induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs) have wide potential application in basic research, drug discovery, and regenerative medicine, but functional maturation remains challenging. Here, we present a method whereby maturation of hiPSC-CMs can be accelerated by simultan...

Descripción completa

Detalles Bibliográficos
Autores principales: Shen, Shi, Sewanan, Lorenzo R., Shao, Stephanie, Halder, Saiti S., Stankey, Paul, Li, Xia, Campbell, Stuart G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9481907/
https://www.ncbi.nlm.nih.gov/pubmed/35931080
http://dx.doi.org/10.1016/j.stemcr.2022.07.006

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9481907/
https://www.ncbi.nlm.nih.gov/pubmed/35931080
http://dx.doi.org/10.1016/j.stemcr.2022.07.006

Ejemplares similares