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Physiological calcium combined with electrical pacing accelerates maturation of human engineered heart tissue

Human-induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs) have wide potential application in basic research, drug discovery, and regenerative medicine, but functional maturation remains challenging. Here, we present a method whereby maturation of hiPSC-CMs can be accelerated by simultan...

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Detalles Bibliográficos
Autores principales:	Shen, Shi, Sewanan, Lorenzo R., Shao, Stephanie, Halder, Saiti S., Stankey, Paul, Li, Xia, Campbell, Stuart G.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9481907/ https://www.ncbi.nlm.nih.gov/pubmed/35931080 http://dx.doi.org/10.1016/j.stemcr.2022.07.006

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