Regulation of male germline transmission patterns by the Trp53-Cdkn1a pathway

A small number of offspring are born from the numerous sperm generated from spermatogonial stem cells (SSCs). However, little is known regarding the rules and molecular mechanisms that govern germline transmission patterns. Here we report that the Trp53 tumor suppressor gene limits germline genetic...

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Detalles Bibliográficos
Autores principales: Kanatsu-Shinohara, Mito, Naoki, Honda, Tanaka, Takashi, Tatehana, Misako, Kikkawa, Takako, Osumi, Noriko, Shinohara, Takashi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9481916/
https://www.ncbi.nlm.nih.gov/pubmed/35931081
http://dx.doi.org/10.1016/j.stemcr.2022.07.007

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9481916/
https://www.ncbi.nlm.nih.gov/pubmed/35931081
http://dx.doi.org/10.1016/j.stemcr.2022.07.007

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