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Co-transport of the nuclear-encoded Cox7c mRNA with mitochondria along axons occurs through a coding-region-dependent mechanism

Nuclear-encoded mitochondrial protein mRNAs have been found to be localized and locally translated within neuronal processes. However, the mechanism of transport for those mRNAs to distal locations is not fully understood. Here, we describe axonal co-transport of Cox7c with mitochondria. Fractionati...

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Detalles Bibliográficos
Autores principales: Cohen, Bar, Altman, Topaz, Golani-Armon, Adi, Savulescu, Anca F., Ibraheem, Amjd, Mhlanga, Musa M., Perlson, Eran, Arava, Yoav S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9481926/
https://www.ncbi.nlm.nih.gov/pubmed/35833493
http://dx.doi.org/10.1242/jcs.259436