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Gain-of-function genetic screens in human cells identify SLC transporters overcoming environmental nutrient restrictions

Solute carrier (SLC) transporters control fluxes of nutrients and metabolites across membranes and thereby represent a critical interface between the microenvironment and cellular and subcellular metabolism. Because of substantial functional overlap, the interplay and relative contributions of SLCs...

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Detalles Bibliográficos
Autores principales: Rebsamen, Manuele, Girardi, Enrico, Sedlyarov, Vitaly, Scorzoni, Stefania, Papakostas, Konstantinos, Vollert, Manuela, Konecka, Justyna, Guertl, Bettina, Klavins, Kristaps, Wiedmer, Tabea, Superti-Furga, Giulio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Life Science Alliance LLC 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9481932/
https://www.ncbi.nlm.nih.gov/pubmed/36114003
http://dx.doi.org/10.26508/lsa.202201404