ALS-linked loss of Cyclin-F function affects HSP90

The founding member of the F-box protein family, Cyclin-F, serves as a substrate adaptor for the E3 ligase Skp1-Cul1-F-box (SCF)(Cyclin-F) which is responsible for ubiquitination of proteins involved in cell cycle progression, DNA damage and mitotic fidelity. Missense mutations in CCNF encoding for...

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Detalles Bibliográficos
Autores principales: Siebert, Alexander, Gattringer, Vanessa, Weishaupt, Jochen H, Behrends, Christian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Life Science Alliance LLC 2022
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9481933/
https://www.ncbi.nlm.nih.gov/pubmed/36114006
http://dx.doi.org/10.26508/lsa.202101359

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9481933/
https://www.ncbi.nlm.nih.gov/pubmed/36114006
http://dx.doi.org/10.26508/lsa.202101359

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