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Accurate prediction of virus-host protein-protein interactions via a Siamese neural network using deep protein sequence embeddings

Prediction and understanding of virus-host protein-protein interactions (PPIs) have relevance for the development of novel therapeutic interventions. In addition, virus-like particles open novel opportunities to deliver therapeutics to targeted cell types and tissues. Given our incomplete knowledge...

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Detalles Bibliográficos
Autores principales: Madan, Sumit, Demina, Victoria, Stapf, Marcus, Ernst, Oliver, Fröhlich, Holger
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9481957/
https://www.ncbi.nlm.nih.gov/pubmed/36124304
http://dx.doi.org/10.1016/j.patter.2022.100551