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Structure-based ligand design and discovery of novel tenuazonic acid derivatives with high herbicidal activity

INTRODUCTION: Computer-aided design has become an important tool to develop novel pesticides based on natural lead compounds. Tenuazonic acid (TeA), a typical representative of the natural tetramic acid family, was patented as a potential bioherbicide. However, its herbicidal efficacy is still not u...

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Detalles Bibliográficos
Autores principales: Wang, He, Yao, Qin, Guo, Yanjing, Zhang, Qian, Wang, Zhongchang, Strasser, Reto Jörg, Valverde, Bernal E., Chen, Shiguo, Qiang, Sheng, Kalaji, Hazem M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9481958/
https://www.ncbi.nlm.nih.gov/pubmed/36100332
http://dx.doi.org/10.1016/j.jare.2021.12.001