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The power and the promise of CRISPR/Cas9 genome editing for clinical application with gene therapy
BACKGROUND: Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR) is derived from the bacterial innate immune system and engineered as a robust gene-editing tool. Due to the higher specificity and efficiency of CRISPR/Cas9, it has been widely applied to many genetic and non-genetic dise...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9481961/ https://www.ncbi.nlm.nih.gov/pubmed/36100322 http://dx.doi.org/10.1016/j.jare.2021.11.018 |