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RSC and GRFs confer promoter directionality by restricting divergent noncoding transcription

The directionality of gene promoters—the ratio of protein-coding over divergent noncoding transcription—is highly variable. How promoter directionality is controlled remains poorly understood. Here, we show that the chromatin remodelling complex RSC and general regulatory factors (GRFs) dictate prom...

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Detalles Bibliográficos
Autores principales: Wu, Andrew CK, Vivori, Claudia, Patel, Harshil, Sideri, Theodora, Moretto, Fabien, van Werven, Folkert J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Life Science Alliance LLC 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9481977/
https://www.ncbi.nlm.nih.gov/pubmed/36114005
http://dx.doi.org/10.26508/lsa.202201394