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RSC and GRFs confer promoter directionality by restricting divergent noncoding transcription
The directionality of gene promoters—the ratio of protein-coding over divergent noncoding transcription—is highly variable. How promoter directionality is controlled remains poorly understood. Here, we show that the chromatin remodelling complex RSC and general regulatory factors (GRFs) dictate prom...
Autores principales: | Wu, Andrew CK, Vivori, Claudia, Patel, Harshil, Sideri, Theodora, Moretto, Fabien, van Werven, Folkert J |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Life Science Alliance LLC
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9481977/ https://www.ncbi.nlm.nih.gov/pubmed/36114005 http://dx.doi.org/10.26508/lsa.202201394 |
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