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NCF4 dependent intracellular reactive oxygen species regulate plasma cell formation

Defective reactive oxygen species (ROS) production by genetically determined variants of the NADPH oxidase 2 (NOX2) complex component, NCF4, leads to enhanced production of autoantibodies to collagen type II (COL2) and severe collagen-induced arthritis (CIA) in mice. To further understand this proce...

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Detalles Bibliográficos
Autores principales: He, Chang, Luo, Huqiao, Coelho, Ana, Liu, Meng, Li, Qijing, Xu, Jing, Krämer, Alexander, Malin, Stephen, Yuan, Zuyi, Holmdahl, Rikard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9482113/
https://www.ncbi.nlm.nih.gov/pubmed/36095971
http://dx.doi.org/10.1016/j.redox.2022.102422