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Specific immunosuppressive role of nanodrugs targeting calcineurin in innate myeloid cells
Calcineurin (CN) inhibitors currently used to avoid transplant rejection block the activation of adaptive immune responses but also prevent the development of tolerance toward the graft, by directly inhibiting T cells. CN, through the transcription factors of the NFAT family, plays an important role...
Autores principales: | , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9482116/ https://www.ncbi.nlm.nih.gov/pubmed/36124235 http://dx.doi.org/10.1016/j.isci.2022.105042 |