Specific immunosuppressive role of nanodrugs targeting calcineurin in innate myeloid cells

Calcineurin (CN) inhibitors currently used to avoid transplant rejection block the activation of adaptive immune responses but also prevent the development of tolerance toward the graft, by directly inhibiting T cells. CN, through the transcription factors of the NFAT family, plays an important role...

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Detalles Bibliográficos
Autores principales: Colombo, Miriam, Marongiu, Laura, Mingozzi, Francesca, Marzi, Roberta, Cigni, Clara, Facchini, Fabio Alessandro, Rotem, Rany, Valache, Mihai, Stucchi, Giulia, Rocca, Giuseppe, Gornati, Laura, Rizzuto, Maria Antonietta, Salvioni, Lucia, Zanoni, Ivan, Gori, Alessandro, Prosperi, Davide, Granucci, Francesca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9482116/
https://www.ncbi.nlm.nih.gov/pubmed/36124235
http://dx.doi.org/10.1016/j.isci.2022.105042

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