Integrative analysis reveals histone demethylase LSD1 promotes RNA polymerase II pausing

Lysine-specific demethylase 1 (LSD1) is well-known for its role in decommissioning enhancers during mouse embryonic stem cell (ESC) differentiation. Its role in gene promoters remains poorly understood despite its widespread presence at these sites. Here, we report that LSD1 promotes RNA polymerase...

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Detalles Bibliográficos
Autores principales: Kim, Hani Jieun, Li, Pishun, Kim, Taiyun, Oldfield, Andrew J., Zheng, Xiaofeng, Yang, Pengyi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9482124/
https://www.ncbi.nlm.nih.gov/pubmed/36124234
http://dx.doi.org/10.1016/j.isci.2022.105049

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9482124/
https://www.ncbi.nlm.nih.gov/pubmed/36124234
http://dx.doi.org/10.1016/j.isci.2022.105049

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