Cargando…

Integrative analysis reveals histone demethylase LSD1 promotes RNA polymerase II pausing

Lysine-specific demethylase 1 (LSD1) is well-known for its role in decommissioning enhancers during mouse embryonic stem cell (ESC) differentiation. Its role in gene promoters remains poorly understood despite its widespread presence at these sites. Here, we report that LSD1 promotes RNA polymerase...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kim, Hani Jieun, Li, Pishun, Kim, Taiyun, Oldfield, Andrew J., Zheng, Xiaofeng, Yang, Pengyi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9482124/ https://www.ncbi.nlm.nih.gov/pubmed/36124234 http://dx.doi.org/10.1016/j.isci.2022.105049

Ejemplares similares

The histone demethylase LSD1/KDM1A promotes the DNA damage response
por: Mosammaparast, Nima, et al.
Publicado: (2013)

A Selective Phenelzine Analogue Inhibitor of Histone Demethylase LSD1
por: Prusevich, Polina, et al.
Publicado: (2014)

Histone demethylase LSD1 controls the phenotypic plasticity of cancer cells
por: Hino, Shinjiro, et al.
Publicado: (2016)

Expanding the Role of the Histone Lysine-Specific Demethylase LSD1 in Cancer
por: Majello, Barbara, et al.
Publicado: (2019)

TRIM28 regulates RNA polymerase II promoter proximal pausing and pause release
por: Bunch, Heeyoun, et al.
Publicado: (2014)

Extranucleosomal DNA enhances the activity of the LSD1/CoREST histone demethylase complex
por: Kim, Sang-Ah, et al.
Publicado: (2015)

Histone Demethylase LSD1 Regulates Kidney Cancer Progression by Modulating Androgen Receptor Activity
por: Lee, Kyoung-Hwa, et al.
Publicado: (2020)

Targeting Histone Demethylase LSD1/KDM1a in Neurodegenerative Diseases
por: Ambrosio, Susanna, et al.
Publicado: (2018)

Lysine-specific histone demethylase 1A (LSD1) in cervical cancer
por: Beilner, Daniel, et al.
Publicado: (2020)

Histone demethylase Lsd1 is required for the differentiation of neural cells in Nematostella vectensis
por: Gahan, James M., et al.
Publicado: (2022)

Targeting Histone Demethylase LSD1 for Treatment of Deficits in Autism Mouse Models
por: Rapanelli, Maximiliano, et al.
Publicado: (2022)

Relationship between histone demethylase LSD family and development and prognosis of gastric cancer
por: Dong, Liyan, et al.
Publicado: (2023)

Histone demethylase LSD1-mediated repression of GATA-2 is critical for erythroid differentiation
por: Guo, Yidi, et al.
Publicado: (2015)

Histone demethylase LSD1 is critical for endochondral ossification during bone fracture healing
por: Sun, Jun, et al.
Publicado: (2020)

Protocol for the processing and downstream analysis of phosphoproteomic data with PhosR
por: Kim, Hani Jieun, et al.
Publicado: (2021)

Histone demethylase LSD1 promotes RIG-I poly-ubiquitination and anti-viral gene expression
por: Hu, Qi-Xin, et al.
Publicado: (2021)

Histone Demethylase LSD1 is required for Germinal Center formation and BCL6-driven lymphomagenesis
por: Hatzi, Katerina, et al.
Publicado: (2018)

Inhibition of Histone Demethylases LSD1 and UTX Regulates ERα Signaling in Breast Cancer
por: Benedetti, Rosaria, et al.
Publicado: (2019)

The histone demethylase Lsd1 regulates multiple repressive gene programs during T cell development
por: Stamos, Daniel B., et al.
Publicado: (2021)

Roles of lysine-specific demethylase 1 (LSD1) in homeostasis and diseases
por: Kim, Dongha, et al.
Publicado: (2021)

Inhibition of the histone demethylase LSD1 blocks α-herpesvirus lytic replication and reactivation from latency
por: Liang, Yu, et al.
Publicado: (2009)

RNA polymerase II pausing in development: orchestrating transcription
por: Abuhashem, Abderhman, et al.
Publicado: (2022)

Histone demethylase Lsd1 represses hematopoietic stem and progenitor cell signatures during blood cell maturation
por: Kerenyi, Marc A, et al.
Publicado: (2013)

Mechanisms and Developmental Roles of Promoter-proximal Pausing of RNA Polymerase II
por: Robinson, Christine, et al.
Publicado: (2016)

Role of RNA Polymerase II Promoter-Proximal Pausing in Viral Transcription
por: Whelan, Marilyn, et al.
Publicado: (2022)

RNA Polymerase II Pausing Downstream of Core Histone Genes Is Different from Genes Producing Polyadenylated Transcripts
por: Anamika, Krishanpal, et al.
Publicado: (2012)

The histone demethylase LSD1 promotes renal inflammation by mediating TLR4 signaling in hepatitis B virus-associated glomerulonephritis
por: Yang, Yi-Tong, et al.
Publicado: (2019)

Genome-wide Single-Molecule Footprinting Reveals High RNA Polymerase II Turnover at Paused Promoters
por: Krebs, Arnaud R., et al.
Publicado: (2017)

Histone demethylase LSD1 regulates bone mass by controlling WNT7B and BMP2 signaling in osteoblasts
por: Sun, Jun, et al.
Publicado: (2018)

Histone demethylase LSD1 restricts influenza A virus infection by erasing IFITM3-K88 monomethylation
por: Shan, Jiaoyu, et al.
Publicado: (2017)

Extra Virgin Olive Oil Contains a Phenolic Inhibitor of the Histone Demethylase LSD1/KDM1A
por: Cuyàs, Elisabet, et al.
Publicado: (2019)

Functional Interaction of Histone Deacetylase 5 (HDAC5) and Lysine-specific Demethylase 1 (LSD1) Promotes Breast Cancer Progression
por: Cao, Chunyu, et al.
Publicado: (2016)

Promoter-proximal pausing of RNA polymerase II: a nexus of gene regulation
por: Core, Leighton, et al.
Publicado: (2019)

The Catalytic-Dependent and -Independent Roles of Lsd1 and Lsd2 Lysine Demethylases in Heterochromatin Formation in Schizosaccharomyces pombe
por: Marayati, Bahjat F., et al.
Publicado: (2020)

Release of promoter–proximal paused Pol II in response to histone deacetylase inhibition
por: Vaid, Roshan, et al.
Publicado: (2020)

Correction: Histone demethylase LSD1 restricts influenza A virus infection by erasing IFITM3-K88 monomethylation
por: Shan, Jiaoyu, et al.
Publicado: (2018)

Correction: Histone demethylase LSD1 restricts influenza A virus infection by erasing IFITM3-K88 monomethylation
por: Shan, Jiaoyu, et al.
Publicado: (2021)

Deletion of histone demethylase Lsd1 (Kdm1a) during retinal development leads to defects in retinal function and structure
por: Ferdous, Salma, et al.
Publicado: (2023)

Splicing- and demethylase-independent functions of LSD1 in zebrafish primitive hematopoiesis
por: Tamaoki, Junya, et al.
Publicado: (2020)

ELL facilitates RNA polymerase II pause site entry and release
por: Byun, Jung S., et al.
Publicado: (2012)

Cannot write session to /tmp/vufind_sessions/sess_610niu3rnr5be9fljceucvkff2