Intratumoral delivered novel circular mRNA encoding cytokines for immune modulation and cancer therapy

The success of the two mRNA vaccines developed by Moderna and BioNTech during the COVID-19 pandemic increased research interest into the application of mRNA technologies. Compared with the canonical linear mRNA used in these vaccines, circular mRNA has been found to mediate more potent and durable p...

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Detalles Bibliográficos
Autores principales: Yang, Jiali, Zhu, Jiafeng, Sun, Jiaojiao, Chen, Yiyun, Du, Yaran, Tan, Yiling, Wu, Linpeng, Zhai, Mengting, Wei, Lixiang, Li, Na, Huang, Ke, Hou, Qiangbo, Tong, Zhenbo, Bechthold, Andreas, Tian, Hao, Sun, Zhenhua, Zuo, Chijian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9482165/
https://www.ncbi.nlm.nih.gov/pubmed/36156907
http://dx.doi.org/10.1016/j.omtn.2022.09.010

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9482165/
https://www.ncbi.nlm.nih.gov/pubmed/36156907
http://dx.doi.org/10.1016/j.omtn.2022.09.010

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