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Mechanobiological responses of astrocytes in optic nerve head due to biaxial stretch

BACKGROUND: Elevated intraocular pressure (IOP) is the main risk factor for glaucoma, which might cause the activation of astrocytes in optic nerve head. To determine the effect of mechanical stretch on the astrocytes, we investigated the changes in cell phenotype, proteins of interest and signaling...

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Detalles Bibliográficos
Autores principales: Li, Zhiwen, Peng, Fan, Liu, Zhicheng, Li, Shanshan, Li, Lin, Qian, Xiuqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9482189/
https://www.ncbi.nlm.nih.gov/pubmed/36114477
http://dx.doi.org/10.1186/s12886-022-02592-8