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Ligands stimulating antitumour immunity as the next G-quadruplex challenge

G-quadruplex (G4) binders have been investigated to discover new anticancer drugs worldwide in past decades. As these ligands are generally not highly cytotoxic, the discovery rational was mainly based on increasing the cell-killing potency. Nevertheless, no G4 binder has been shown yet to be effect...

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Detalles Bibliográficos
Autores principales: Miglietta, Giulia, Marinello, Jessica, Russo, Marco, Capranico, Giovanni
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9482198/
https://www.ncbi.nlm.nih.gov/pubmed/36114513
http://dx.doi.org/10.1186/s12943-022-01649-y