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Peroxisome proliferator-activated receptor gamma gene variants modify human airway and systemic responses to indoor dibutyl phthalate exposure

BACKGROUND: Single nucleotide polymorphisms (SNPs) of peroxisome proliferator-activated receptor gamma (PPAR-γ; gene: PPARG) and oxidative stress genes are associated with asthma risk. However, whether such variants modulate responses to dibutyl phthalate (DBP), a common plasticizer associated with...

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Detalles Bibliográficos
Autores principales: Leung, Clarus, Ryu, Min Hyung, Bølling, Anette Kocbach, Maestre-Batlle, Danay, Rider, Christopher F., Hüls, Anke, Urtatiz, Oscar, MacIsaac, Julie L., Lau, Kevin Soon-Keen, Lin, David Tse Shen, Kobor, Michael S., Carlsten, Chris
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9482266/
https://www.ncbi.nlm.nih.gov/pubmed/36114491
http://dx.doi.org/10.1186/s12931-022-02174-8