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Cumulative effect of simvastatin, l-arginine, and tetrahydrobiopterin on cerebral blood flow and cognitive function in Alzheimer’s disease

BACKGROUND AND OBJECTIVES: Vascular disease is a known risk factor for Alzheimer’s disease (AD). Endothelial dysfunction has been linked to reduced cerebral blood flow. Endothelial nitric oxide synthase pathway (eNOS) upregulation is known to support endothelial health. This single-center, proof-of-...

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Detalles Bibliográficos
Autores principales: Degrush, Elizabeth, Shazeeb, Mohammed Salman, Drachman, David, Vardar, Zeynep, Lindsay, Clifford, Gounis, Matthew J., Henninger, Nils
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9482313/
https://www.ncbi.nlm.nih.gov/pubmed/36115980
http://dx.doi.org/10.1186/s13195-022-01076-7