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Cumulative effect of simvastatin, l-arginine, and tetrahydrobiopterin on cerebral blood flow and cognitive function in Alzheimer’s disease
BACKGROUND AND OBJECTIVES: Vascular disease is a known risk factor for Alzheimer’s disease (AD). Endothelial dysfunction has been linked to reduced cerebral blood flow. Endothelial nitric oxide synthase pathway (eNOS) upregulation is known to support endothelial health. This single-center, proof-of-...
Autores principales: | Degrush, Elizabeth, Shazeeb, Mohammed Salman, Drachman, David, Vardar, Zeynep, Lindsay, Clifford, Gounis, Matthew J., Henninger, Nils |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9482313/ https://www.ncbi.nlm.nih.gov/pubmed/36115980 http://dx.doi.org/10.1186/s13195-022-01076-7 |
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