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Retinoic acid delays initial photoreceptor differentiation and results in a highly structured mature retinal organoid
BACKGROUND: Human-induced pluripotent stem cell-derived retinal organoids are a valuable tool for disease modelling and therapeutic development. Many efforts have been made over the last decade to optimise protocols for the generation of organoids that correctly mimic the human retina. Most protocol...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9482314/ https://www.ncbi.nlm.nih.gov/pubmed/36114559 http://dx.doi.org/10.1186/s13287-022-03146-x |