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Retinoic acid delays initial photoreceptor differentiation and results in a highly structured mature retinal organoid

BACKGROUND: Human-induced pluripotent stem cell-derived retinal organoids are a valuable tool for disease modelling and therapeutic development. Many efforts have been made over the last decade to optimise protocols for the generation of organoids that correctly mimic the human retina. Most protocol...

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Detalles Bibliográficos
Autores principales: Sanjurjo-Soriano, Carla, Erkilic, Nejla, Damodar, Krishna, Boukhaddaoui, Hassan, Diakatou, Michalitsa, Garita-Hernandez, Marcela, Mamaeva, Daria, Dubois, Gregor, Jazouli, Zhour, Jimenez-Medina, Carla, Goureau, Olivier, Meunier, Isabelle, Kalatzis, Vasiliki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9482314/
https://www.ncbi.nlm.nih.gov/pubmed/36114559
http://dx.doi.org/10.1186/s13287-022-03146-x