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TGF-β signaling in the tumor metabolic microenvironment and targeted therapies

Transforming growth factor-β (TGF-β) signaling has a paradoxical role in cancer progression, and it acts as a tumor suppressor in the early stages but a tumor promoter in the late stages of cancer. Once cancer cells are generated, TGF-β signaling is responsible for the orchestration of the immunosup...

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Detalles Bibliográficos
Autores principales: Shi, Xueke, Yang, Jin, Deng, Shuzhi, Xu, Hongdan, Wu, Deyang, Zeng, Qingxiang, Wang, Shimeng, Hu, Tao, Wu, Fanglong, Zhou, Hongmei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9482317/
https://www.ncbi.nlm.nih.gov/pubmed/36115986
http://dx.doi.org/10.1186/s13045-022-01349-6