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UBE3D Is Involved in Blue Light-Induced Retinal Damage by Regulating Double-Strand Break Repair

PURPOSE: Age-related macular degeneration (AMD) is currently the leading cause of blindness worldwide. Previously, we identified ubiquitin-protein ligase E3D (UBE3D) as an AMD-associated protein for East Asian populations, and here we further demonstrate that UBE3D could be associated with DNA damag...

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Detalles Bibliográficos
Autores principales: Xu, Ningda, Liu, Yue, Nai, Shanshan, Tao, Yong, Ding, Yuehe, Jia, Lemei, Geng, Qizhi, Li, Jie, Bai, Yujing, Wei, Gong-Hong, Dong, Meng-Qiu, Luo, Linyi, Zhao, Mingwei, Xu, Xingzhi, Li, Xiao-Xin, Li, Jing, Huang, Lvzhen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9482326/
https://www.ncbi.nlm.nih.gov/pubmed/36094642
http://dx.doi.org/10.1167/iovs.63.10.7