H3K9 tri-methylation at Nanog times differentiation commitment and enables the acquisition of primitive endoderm fate

Mouse embryonic stem cells have an inherent propensity to explore gene regulatory states associated with either self-renewal or differentiation. This property depends on ERK, which downregulates pluripotency genes such as Nanog. Here, we aimed at identifying repressive histone modifications that wou...

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Detalles Bibliográficos
Autores principales: Dubois, Agnès, Vincenti, Loris, Chervova, Almira, Greenberg, Maxim V. C., Vandormael-Pournin, Sandrine, Bourc'his, Déborah, Cohen-Tannoudji, Michel, Navarro, Pablo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2022
Materias:
Stem Cells and Regeneration
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9482333/
https://www.ncbi.nlm.nih.gov/pubmed/35976266
http://dx.doi.org/10.1242/dev.201074

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9482333/
https://www.ncbi.nlm.nih.gov/pubmed/35976266
http://dx.doi.org/10.1242/dev.201074

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