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Computational Model of the Effect of Mitochondrial Dysfunction on Excitation–Contraction Coupling in Skeletal Muscle

It has become well established that mitochondria not only regulate myoplasmic calcium in skeletal muscle, but also use that calcium to stimulate oxidative phosphorylation (OXPHOS). While experimental approaches have allowed for imaging of mitochondrial calcium and membrane potentials in isolated fib...

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Detalles Bibliográficos
Autores principales: Senneff, Sageanne, Lowery, Madeleine M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9482608/
https://www.ncbi.nlm.nih.gov/pubmed/36114931
http://dx.doi.org/10.1007/s11538-022-01079-3