Protein tyrosine kinase inhibitor resistance in malignant tumors: molecular mechanisms and future perspective

Protein tyrosine kinases (PTKs) are a class of proteins with tyrosine kinase activity that phosphorylate tyrosine residues of critical molecules in signaling pathways. Their basal function is essential for maintaining normal cell growth and differentiation. However, aberrant activation of PTKs cause...

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Detalles Bibliográficos
Autores principales: Yang, Yang, Li, Shuo, Wang, Yujiao, Zhao, Yi, Li, Qiu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9482625/
https://www.ncbi.nlm.nih.gov/pubmed/36115852
http://dx.doi.org/10.1038/s41392-022-01168-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9482625/
https://www.ncbi.nlm.nih.gov/pubmed/36115852
http://dx.doi.org/10.1038/s41392-022-01168-8

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