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Mechanistic understanding of human SLFN11

Schlafen 11 (SLFN11) is an interferon-inducible antiviral restriction factor with tRNA endoribonuclease and DNA binding functions. It is recruited to stalled replication forks in response to replication stress and inhibits replication of certain viruses such as the human immunodeficiency virus 1 (HI...

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Detalles Bibliográficos
Autores principales: Metzner, Felix J., Wenzl, Simon J., Kugler, Michael, Krebs, Stefan, Hopfner, Karl-Peter, Lammens, Katja
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9482658/
https://www.ncbi.nlm.nih.gov/pubmed/36115853
http://dx.doi.org/10.1038/s41467-022-33123-0