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Mechanistic understanding of human SLFN11
Schlafen 11 (SLFN11) is an interferon-inducible antiviral restriction factor with tRNA endoribonuclease and DNA binding functions. It is recruited to stalled replication forks in response to replication stress and inhibits replication of certain viruses such as the human immunodeficiency virus 1 (HI...
Autores principales: | Metzner, Felix J., Wenzl, Simon J., Kugler, Michael, Krebs, Stefan, Hopfner, Karl-Peter, Lammens, Katja |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9482658/ https://www.ncbi.nlm.nih.gov/pubmed/36115853 http://dx.doi.org/10.1038/s41467-022-33123-0 |
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