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METTL3 dual regulation of the stability of LINC00662 and VEGFA RNAs promotes colorectal cancer angiogenesis

PURPOSE: The angiogenesis is among the primary factors that affect tumor recurrence and distant organ metastasis in colorectal cancer (CRC). N6-methyladenosine (m6A) modification is one of the most common chemical modifications in eukaryotic mRNA, especially at the post-transcriptional level. Methyl...

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Detalles Bibliográficos
Autores principales: Zhang, Guoying, Wang, Tianjun, Huang, Zihui, Chen, Yuanyuan, Sun, Li, Xia, Xia, He, Fang, Fan, Chenying, Wang, Shukui, Liu, Wanli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9482670/
https://www.ncbi.nlm.nih.gov/pubmed/36114893
http://dx.doi.org/10.1007/s12672-022-00557-3